Antimalarial activity of thiophenyl- and benzenesulfonyl-dihydroartemisinin.
نویسندگان
چکیده
Each diastereomer of 10-thiophenyl- and 10-benzenesulfonyl-dihydroartemisinin was synthesized from artemisinin in three steps, and screened against chloroquine-resistance and chloroquine-sensitive Plasmodium falciparum. Three of the four tested compounds were found to be effective. Especially, 10 beta-benzenesulfonyl-dihydroartemisinin showed stronger antimalarial activity than artemisinin.
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عنوان ژورنال:
- The Korean journal of parasitology
دوره 43 3 شماره
صفحات -
تاریخ انتشار 2005